ANGLE (AGL ) shares jump 60.91% to 158.5p as it receives first of its kind FDA clearance

The liquid biopsy company has received clearance from the US Food and Drug Administration for the Parsortix® system and its intended use with metastatic breast cancer (MBC) patients.

The clearance, which is the global gold standard for medical devices, from the US FDA is the first ever FDA product clearance to harvest cancer cells from a patient blood sample for subsequent analysis and offers the prospect of a new era of personalised cancer care.

ANGLE intends to use Parsortix®  to support the entire medical industry in its adoption of liquid biopsy solutions for repeat non-invasive diagnostics for personalised cancer care.

Caspian Sunrise (CASP ) shares jump 44.83% to 4.2p as it successfully re-drills Well 142

Today, the company reported on the successful workover of Well 142 on the MJF structure, which has added a further approximately 1,400 bopd (at 8mm choke) to the BNG production capacity, which including the existing South Yelemes wells, is now approximately 4,000 bopd.

Well 142, which is the latest of a number existing wells to be re-drilled using a horizontal drilling approach, was drilled to 1,984m with a horizontal spur of 90 metres into the interval.

The company said it believes that its ongoing programme of drilling and re-drilling shallow wells using a horizontal drilling approach should result in reaching a production capacity solely from the shallow structures at the BNG Contract Area of 5,000 bopd this year.

Poolbeg Pharma (POLB ) shares see relief, climbing back up 19.59% to 5.8p

Despite shares in Poolbeg Pharma having dipped by over 20% in the past week, shares have now climbed back up with the stock reaching highs of 5.9 during Wednesday morning trading.

In May, Poolbeg has signed a GMP manufacturing agreement ensuring the ample supply of its lead asset, POLB 001 which aims to address a significant unmet need in severe influenza.

Poolbeg is targeting the infectious disease market which, in the wake of the pandemic, has become one of the fastest growing markets and is expected to exceed $250 billion by 2025.

Randall & Quilter Investments (RQIH ) shares fall 41.67% to 80p as bidder backs out

Shares in the insurance company reached lows of 79.4p today after a proposed £482 million takeover and US$100 million fundraising came into question as the company revealed that Brickell PC Insurance Holdings LLC wants to exercise its right to terminate its £482m offer.

Randall & Quilter said it had received a letter from Brickell alleging that it was in breach of certain obligations under the terms of the deal, and as a result, was terminating its offer.

The Company, which stated that it has not breached these terms in any way, told investors that it would be adjourning a special meeting at some point today to agree to the acquisition, unless it receives indications that shareholders would vote against the necessary resolutions.

RQL