Amryt Pharma Plc shares rose 43.75% to 230p after reporting positive trial results
The biopharmaceutical group reported “very positive” results from its Phase 3 EASE trial, the largest international clinical trial conducted in patients with Epidermolysis Bullosa (EB).
The outcome marks an important milestone as it seeks approval for FILSUVEZ®, a potential treatment for EB, a rare genetic condition for which there is no approved treatment.
If FILSUVEZ®, formerly known as AP101 /Oleogel-S10 is approved, Amryt said it will leverage its existing global infrastructure to commercialise the product as a treatment for EB.
The primary endpoint of the trial achieved ‘statistical significance’ compared to a control gel. Amryt said this represents the first ever successful Phase 3 top line readout in EB.
The global market opportunity for EB is estimated by Amryt to be in excess of $1 billion.
“We are proud to present these positive and encouraging results, demonstrating that FILSUVEZ® could make an important difference to the lives of patients,” said CEO, Dr Joe Wiley.
Somero Enterprises Plc shares jumped 24.10% at 257.5p after passing “stress test”
The manufacturer of laser-guided equipment said the pandemic has served as an excellent ‘stress test’ for the business and that it has begun the second half of 2020 ‘with confidence’.
The group said it sees confidence in the strength of its financial position, in the flexibility of its operating model and in the demand it has seen for its recently launched products.
The Board has declared an interim dividend of US$ 0.040 cents per share. Looking ahead, Somero stated that it expects second half trading volumes to improve from the first half.
“We begin the second half of the year with confidence in the strength of our financial position, in the flexibility of our operating model, and in the demand seen for our recently launched products,” said Jack Cooney, Chief Executive of Somero.
PowerHouse Energy Group Plc shares increased 10.00% at 3.3p following a £5m raise
The company focused on hydrogen production from waste plastic raised £5m at 2.5p. The group believes the funds will provide the necessary cash resources to reach profitability.
The proceeds will be used to refine technical aspects and assist development company, Peel Environmental, to deliver the first commercial-scale DMG® installation at the Protos plant.
The company recently said that plans to build the UK’s first waste plastic to hydrogen facility were advancing with the completion of a Front-End Engineering Design (FEED) phase.
Peel L&P claims that the approach could revolutionise the way that 4.9 million tonnes of plastic waste generated in the UK each year is handled, as reported by The Engineer.
Construction at the Protos power plant is now expected to commence at the end of 2020.
“The Board is confident this funding will facilitate Powerhouse to complete the first projects, reach profitability and roll out its international growth strategy,” said Dr Cameron Davies, Chairman of Powerhouse, adding that the fundraising was oversubscribed.
Thor Mining shares were trading 7.14% higher at 0.675p after completing acquisition
The AIM-listed resources company said it has now completed its acquisition of 100% of American Vanadium (AVU) including its subsidiaries and uranium and vanadium projects.
AVU holds interests in uranium and vanadium-focused projects across Colorado and Utah in the US and will be acquired through the issue of 24 million ordinary Thor shares at 0.01p.
Specifically, the Colorado project claims include historical mines with historical production activity over a period of more than 100 years while Utah project claims have previously reported historical drilling with significant intersections of uranium and vanadium.
Mick Billing, Executive Chairman of Thor Mining, said the company now has “a well balanced portfolio of very attractive assets with copper, gold, tungsten & now uranium & vanadium.”
Blue Star Capital shares were trading 4.44% higher at 0.235p following LSE flotation
Blue Star’s investee company Guild Esports, in which it holds 11.7% in, has announced its intention to seek admission to the standard segment of the Official List of the UK Listing Authority and to trade on the main market of the London Stock Exchange later this year.
The online gaming firm which is co-owned by David Beckman expects to be the first esports franchise to join the LSE and plans to raise £20 million in its London stock market listing.
Roughly 40% of the company’s shares will be available through the listing, according to another person briefed on the plans, the Financial Times reported this morning.
Guild Esports said the online gaming market is projected to grow to 646m viewers by 2023. The growth in viewers has been matched by revenue generated by esports, increasing from $130m in 2012 to an estimated US$1.1bn in 2020. It is projected to reach $1.55bn by 2023.
Guild said it initially plans to set up and field dedicated teams to compete in four online games: Fortnite; CS:Go; Rocket League and FIFA. It said David Beckham will use his global influence and following ‘to support the development of the company’s brand and business.’
The company said it intends to engage up to 20 esports players by the end of 2021.